TABLE 2.
Association of cannabis use with IQ changes in unadjusted and adjusted linear regression analyses (n = 5162).
| Unadjusted | Model 1 a | Model 2 b | Model 3 c | Model 4 d | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| b [95% CI] e | R 2 | p value | b [95% CI] e | R 2 | p value | b [95% CI] e | R 2 | p value | b [95% CI] e | R 2 | p value | b [95% CI] e | R 2 | p value | |
| Use of cannabis | 0.006 | 0.191 | 0.202 | 0.206 | 0.213 | ||||||||||
| Nonusers (n = 3134) | Ref. | — | Ref. | — | Ref. | — | Ref. | — | Ref. | — | |||||
| Users (n = 2028) | 1.53 [0.99, 2.08] | <0.001 | 1.37 [0.88, 1.87] | <0.001 | 1.26 [0.69, 1.83] | <0.001 | 1.58 [1.09, 2.07] | <0.001 | 1.28 [0.71, 1.85] | <0.001 | |||||
a
Model 1: Age at follow‐up, retest interval, IQ at conscription, years of education.
b
Model 2: Age at follow‐up, retest interval, IQ at conscription, years of education, years of weekly extreme binge drinking, use of other illicit drugs, smoking.
c
Model 3: Age at follow‐up, retest interval, IQ at conscription, years of education, psychiatric disorders, CCI.
d
Model 4: Fully adjusted model.
e
Positive numbers indicate less change in IQ scores from baseline to follow‐up compared to the change observed in the reference group, while negative numbers indicate a larger change in IQ scores compared to the reference group.