Table 1.

Characteristics of the animals and effects of CXCR7 mAb treatment.

	Control	Control + CXCR7	DOCA-UNX	DOCA-UNX + CXCR7
Group size	7	7	6	6
Body weight (BW) (g)	27.9 ± 0.8	28.8 ± 0.6	26.5 ± 0.9	26.3 ± 0.9
Heart weight (HW) (mg)	144 ± 8	153 ± 9	186 ± 14*	175 ± 7
HW/BW (mg/g)	5.2 ± 0.2	5.3 ± 0.2	7.07 ± 0.7*	6.7 ± 0.4
Kidney weight (KW) (mg)	306 ± 24	310 ± 15	582 ± 35*	489 ± 30*
KW/BW (mg/g)	10.9 ± 0.6	10.7 ± 0.4	21.9 ± 1.0*	16.3 ± 3.0*
Lung weight (LW) (mg)	168 ± 8	188 ± 7	198 ± 22	177 ± 7
LW/BW (mg/g)	6.0 ± 0.2	6.5 ± 0.2	7.6 ± 1.0	6.7 ± 0.2
Tibia length (TL) (mm)	17.4 ± 0.1	17.4 ± 0.1	16.9 ± 0.1*	17.2 ± 0.2
Plasma Cr (µg/dL)	61 ± 5	60 ± 8	43 ± 6*	45 ± 6*
Urine volume (ml) (24 h)	1.4 ± 0.3	1.3 ± 0.3	28.0 ± 4.7*	6.2 ± 1.8*#

All data were presented as the mean ± SEM. *p < 0.05 vs. Control. ^#p < 0.05 vs. DOCA-UNX.