TABLE 1.
Demographics and clinical features of South Asian PSP patients (n = 27)*
| Age at onset, mean (SD) | 63.8 (7.0) |
| Young‐onset (<60 years), n (%) | 6 (22) |
| Male, n (%) | 14 (52) |
| Ethnicity, n (%) | |
| Indian | 21 (78) |
| Pakistani | 3 (11) |
| Sri Lankan | 3 (11) |
| PSP predominance type, n (%) | |
| RS | 18 (67) |
| PGF | 4 (15) |
| P | 4 (15) |
| F | 1 (4) |
| Presenting symptoms, n (%) | |
| Parkinsonism | 15 (56) |
| Falls | 9 (33) |
| Cognitive dysfunction | 10 (37) |
| Dysarthria | 7 (26) |
| Cerebellar signs, n (%) | 9 (33) |
| Nystagmus | 4 (15) |
| Limb dysmetria | 4 (15)*** |
| Gait ataxia | 1 (4) |
| Hypermetric saccades | 1 (4) |
| Other features, n (%) | |
| REM sleep behavior disturbance; n = 20** | 11 (55) |
| Visual hallucinations | 6 (22) |
| Abnormal posture | 3 (11) |
| Dysautonomia | 2 (7) |
| Levodopa responsiveness, n (%) | 7 (26) |
| Levodopa‐induced dyskinesia, n (%) | 3 (11) |
| Family history of parkinsonism, n (%); n = 25** | 5 (20) |
Abbreviations: F: frontal lobe cognitive or behavioral presentations; P: parkinsonism; PGF: progressive gait freezing; PSP: progressive supranuclear palsy; REM: rapid eye movement; RS: Richardson's syndrome.
*
Unless specified otherwise.
**
Information available when specifically enquired about.
***
1 patient had both nystagmus and limb dysmetria.