Table 4.
Estimated PK characteristics of azithromycin after 3 days of treatment
| Dose group (mg/kg) | Cmax (mg/L) | CV (%) | Tmax (h) | CV (%) | AUC0-24 h (mg*h/L) | CV (%) |
|---|---|---|---|---|---|---|
| 10 | 0.21 | 86 | 2.75 | 40 | 2.24 | 40 |
| 15 | 0.40 | 74 | 2.50 | 46 | 3.56 | 37 |
| 20 | 0.48 | 65 | 2.74 | 36 | 4.74 | 39 |
Values reported as geometric mean ± geometric coefficient of variation (CV). Cmax, maximum concentration; Tmax, time after dose at which maximum concentration is reached; AUC0-24 h, estimated area under the concentration time curve over 24 h on the third day of treatment