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(A) Fine-needle aspiration of a secretory carcinoma is shown. By immunohistochemistry, secretory carcinoma cells are (B) negative for nuclear receptor subfamily 4 group A member 3 (NR4A3) and (C) negative for DOG1. (D) By fluorescence in situ hybridization, the tumor cells are negative for NR4A3 rearrangement, showing a lack of break-apart signal (H&E stain; original magnification ×200 in A-C, ×400 in D).
