The binding energy of the most active compounds in comparison to the co-crystallized ligand for each prospective target.

No.	Compound	EGFR	HER-2	TOP-II	Aromatase
1	13c	−8.0	−10.4	−10.7	−9.9
2	11e	−7.9	−8.9	−9.5	−9.1
3	7c	−7.7	−10.3	−10.2	−10.6
4	Co-crystallized ligand in EGFR	−8.1	—	—	—
5	Co-crystallized ligand in HER-2	—	−11.6	—	—
6	Co-crystallized ligand in Top-II	—	—	−10.9	—
7	Co-crystallized ligand in aromatase	—	—	—	−10.7