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. Author manuscript; available in PMC: 2024 Nov 7.
Published in final edited form as: Eur Spine J. 2023 May 17;32(7):2358–2367. doi: 10.1007/s00586-023-07739-9

Table 4.

T2 values of the NP and the AF by donor age group and disc level. The mean and standard error of the mean at the (A) NP and (B) AF, and (C) counts. Results of random effects linear regression models for (D) NP and (E) AF.

A. Mean ± Standard Error of T2 value of the NP
Age L1–2 L2–3 L3–4 L4–5 Total

<40 124.1 ± 7.3 110.7 ± 7.6 93.8 ± 19.2 97.5 ± 21.5 106.6 ± 7.5
40–49 91.1 ± 13.8 89.9 ± 6.5 80.3 ± 13.4 91.7 ± 13.1 88.2 ± 5.5
50–59 80.0 ± 4.1 70.1 ± 2.8 67.1 ± 2.9 71.8 ± 3.1 72.3 ± 1.7
60–69 73.5 ± 4.5 67.7 ± 4.4 62.8 ± 2.8 62.6 ± 2.4 66.7 ± 1.9
70+ 69.2 ± 7.4 56.6 ± 3.3 59.7 ± 4.7 59.0 ± 4.1 61.1 ± 2.6

all ages 79.6 ± 2.9 71.0 ± 2.4 67.0 ± 2.2 69.7 ± 2.4 71.8 ± 1.3
B. Mean ± Standard Error of T2 value of the AF
Age L1–2 L2–3 L3–4 L4–5 Total

<40 42.0 ± 3.4 34.9 ± 1.3 32.0 ± 0.9 33.3 ± 1.3 35.6 ± 1.3
40–49 38.3 ± 4.4 37.8 ± 2.8 35.3 ± 1.3 36.9 ± 1.4 37.1 ± 1.3
50–59 39.7 ± 1.2 37.3 ± 0.9 36.2 ± 0.7 40.3 ± 1.3 38.4 ± 0.5
60–69 38.4 ± 1.4 34.8 ± 1.0 35.5 ± 1.0 36.7 ± 1.0 36.3 ± 0.6
70+ 43.3 ± 5.8 36.2 ± 3.0 40.6 ± 4.4 44.4 ± 3.7 41.1 ± 2.2

all ages 39.8 ± 1.0 36.2 ± 0.6 36.2 ± 0.7 39.0 ± 0.9 37.8 ± 0.4
C. Counts
Age L1–2 L2–3 L3–4 L4–5 Total

<40 4 4 4 4 16
40–49 4 4 4 4 16
50–59 29 30 30 30 119
60–69 24 24 23 24 95
70+ 9 9 9 9 36

all ages 70 71 70 71 282
D. Linear regression: T2 of NP as a function of disc level, age, and sex
Factors Value Std. Error DF t-value p-value
Intercept 126.5 9.6 209 13.2 <0.001
L1–2 9.9 2.6 209 3.8 <0.001
L2–3 1.3 2.6 209 0.5 0.609
L3–4 −2.7 2.6 209 −1.1 0.292
(Ref. L4–5)
Age −1.0 0.2 68 −6.5 <0.001
Sex (M) 4.9 3.8 68 1.3 0.205
E. Linear regression: T2 of AF as a function of disc level, age, and sex
Factors Value Std. Error DF t-value p-value
Intercept 34.9 3.8 208 9.1 <0.001
L1–2 0.8 0.9 208 0.8 0.403
L2–3 −2.8 0.9 208 −3.1 0.002
L3–4 −2.8 0.9 208 −3.1 0.002
(Ref. L4–5)
Age 0.1 0.1 68 1.4 0.171
Sex (M) −1.4 1.5 68 −0.9 0.373