Table 2.
Physicochemical descriptors obtained by chromatographic data. A/B: acid or base profile. ND: not determined.
| Compound | Absorption | A/B | BR log D | log kwIAM | Δ log kwIAM | Chamelogk |
|---|---|---|---|---|---|---|
| ARV-110 | Oral | Base | 4.25 | 3.20 | 0.33 | 0.99 |
| ARV-471 | Oral | Base | 4.73 | 3.39 | 0.07 | 1.35 |
| DT2216 | Intravenous | Ampholite | > 6 | > 4 | ND | ND |