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. 2024 Aug 27;12(5):721–736. doi: 10.5599/admet.2334

Table 2.

Physicochemical descriptors obtained by chromatographic data. A/B: acid or base profile. ND: not determined.

Compound Absorption A/B BR log D log kwIAM Δ log kwIAM Chamelogk
ARV-110 Oral Base 4.25 3.20 0.33 0.99
ARV-471 Oral Base 4.73 3.39 0.07 1.35
DT2216 Intravenous Ampholite > 6 > 4 ND ND