Table 1. Baseline demographic and disease characteristics.
| Characteristics | All (n = 91) | Nonchemotherapy (n = 50) | Chemotherapy (n = 41) | p Value |
|---|---|---|---|---|
| Sex, n (%) | ||||
| Male | 45 (49.45%) | 19 (38.00%) | 26 (63.41%) | 0.016 |
| Female | 46 (50.55%) | 31 (62.00%) | 15 (36.59%) | |
| Age, years, mean ± SD | 60.76 ± 11.78 | 59.48 ± 12.16 | 62.48 ± 11.62 | 0.234 |
| BMI, mean ± SD | 23.44 ± 4.48 | 23.21 ± 4.29 (n = 48) | 23.50 ± 4.76 | 0.843 |
| Smoking, n (%) | 19 (20.88%) | 7 (14.00%) | 12 (29.27%) | 0.075 |
| Primary cancer, n (%) | ||||
| GI | 32 (35.16%) | 11 (22.00%) | 21 (51.22%) | 0.009 |
| HBP | 15 (16.58%) | 8 (16.00%) | 7 (17.07%) | |
| Breast | 25 (27.47%) | 20 (40.00%) | 5 (12.20%) | |
| Prostate | 5 (5.49%) | 2 (4.00%) | 3 (7.32%) | |
| Others | 14 (15.38%) | 9 (18.00%) | 5 (12.20%) | |
| Metastatic disease, n (%) | 44 (48.35%) | 17 (34.00%) | 27 (65.85%) | 0.002 |
| Comorbid, n (%) | ||||
| DM | 17 (18.68%) | 9 (18.00%) | 8 (19.51%) | 0.854 |
| HT | 34 (37.46%) | 15 (30.00%) | 19 (46.34%) | 0.109 |
| Other | 40 (43.96%) | 20 (40.00%) | 20 (48.78%) | 0.401 |
| Vaccines, n (%) | ||||
| mRNA+mRNA | 41 (45.05%) | 21 (42.00%) | 20 (48.78%) | 0.688 |
| Non-mRNA+mRNA | 19 (20.88%) | 12 (24.00%) | 7 (17.07%) | |
| Non-mRNA+non-mRNA | 31 (34.07%) | 17 (34.00%) | 14 (34.15%) | |
| Third vaccine booster | 21 (23.08%) | 12 (24.00%) | 9 (21.95%) | 0.817 |
| WBC count, cells/mm3, median (IQR) | 5985 (4400–7280) | 6270 (4730–7540) | 5040 (4160–6350) | 0.085 |
| Neutrophil count, cells/mm3, median (IQR) | 3085 (2430–4190) | 3560 (2520–4190) | 2840 (2300–4560) | 0.231 |
| Lymphocyte count, cells/mm3, median (IQR) | 1720 (1210–2270) | 1870 (1370–2570) | 1490 (950–1910) | 0.057 |
| Hematologic AE during follow up | ||||
| Leukopenia | 15 (24.19%) | 4 (12.9%) | 11 (35.48%) | 0.038 |
| Neutropenia | 5 (8.06%) | 0 | 5 (16.13%) | 0.020 |
| Lymphopenia | 20 (32.26%) | 7 (22.58%) | 13 (41.94%) | 0.103 |
BMI = body mass index (mg/m2), GI = gastrointestinal cancer, HBP = hepatobiliary-pancreatic cancer, DM = diabetes mellitus, HT = hypertension, WBC = white blood cell, AE = adverse event