Comparison 5. Treatment‐related mortality.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 All trials (previously untreated patients)	4	941	Risk Ratio (M‐H, Random, 95% CI)	1.28 [0.25, 6.61]
2 Rituximab‐containing regimen (previously untreated patients)	4	941	Risk Ratio (M‐H, Random, 95% CI)	1.28 [0.25, 6.61]
2.1 Rituximab in both arms	1	134	Risk Ratio (M‐H, Random, 95% CI)	1.46 [0.25, 8.44]
2.2 No rituximab in both arms	3	807	Risk Ratio (M‐H, Random, 95% CI)	0.97 [0.04, 26.11]