TABLE 2.
Adverse Events
| Event | Adverse Events Regardless of Attribution, No. (%) | Treatment-Related Adverse Events, No. (%) | ||||
|---|---|---|---|---|---|---|
| Grade 1-2 | Grade 3 | Grade 4 | Grade 1-2 | Grade 3 | Grade 4 | |
| Any adverse events | 62 (100) | 33 (53) | 5 (8) | 59 (95) | 26 (42) | 5 (8) |
| Nausea | 36 (58) | 1 (2) | 0 | 35 (56) | 1 (2) | 0 |
| Decreased appetite | 30 (48) | 4 (6) | 0 | 30 (48) | 3 (5) | 0 |
| Malaise | 26 (42) | 0 | 0 | 25 (40) | 0 | 0 |
| Anemia | 11 (18) | 14 (23) | 0 | 11 (18) | 13 (21) | 0 |
| Decreased neutrophil count | 8 (13) | 8 (13) | 4 (6) | 8 (13) | 8 (13) | 4 (6) |
| Decreased white blood cell count | 12 (19) | 6 (10) | 2 (3) | 12 (19) | 6 (10) | 2 (3) |
| Constipation | 17 (27) | 0 | 0 | 8 (13) | 0 | 0 |
| Pneumonitis/ILD | 15 (24) | 1 (2) | 0 | 15 (24) | 1 (2) | 0 |
| Pyrexia | 14 (23) | 1 (2) | 0 | 7 (11) | 0 | 0 |
| Decreased platelet count | 10 (16) | 3 (5) | 2 (3) | 10 (16) | 3 (5) | 2 (3) |
| Stomatitis | 14 (23) | 0 | 0 | 14 (23) | 0 | 0 |
| Diarrhea | 12 (19) | 1 (2) | 0 | 8 (13) | 1 (2) | 0 |
| Vomiting | 11 (18) | 0 | 0 | 10 (16) | 0 | 0 |
Abbreviation: ILD, interstitial lung disease.