Table 1. Selected data for base case.

Data inputs			Expected value (CAD)	Range
Cost inputs
	Radical hysterectomy (open) [19]		$7,732	$5,412–$10,052
	Radical hysterectomy (MIS) [19]		$4,151	$2,906–$5,396
	Robotic hysterectomy [26]		$13,012	$9,108–$16,916
	Simple hysterectomy (open) [19]		$5,276	$3,693–$6,859
	Simple hysterectomy (MIS) [19]		$4,151	$2,906–$5,396
	Urinary tract complication requiring Urology [19]		$8,220	$5,754–$10,686
	Intestinal complication requiring General Surgery [19]		$7,095	$4,967–$9,224
Postoperative complications requiring readmission to hospital [19]
	Bowel obstruction		$3,529	$2,470–$4,588
	Pulmonary embolism		$5,098	$3,568–$6,627
	Deep vein thrombosis/thrombophlebitis		$4,954	$3,468–$6,440
Outpatient visits [20]
	Initial consultation (gynecologic oncologist, radiation or medical oncologist)		$155	$108–$202
	Follow-up visit		$85	$60–$111
	Consultation in emergency department for postoperative complication		$130	$91–$169
	CT scan abdomen and pelvis		$139	$97–$181
	Biopsy vaginal vault for suspected recurrence		$52	$36–$68
	Interventional radiology consultation for other biopsy		$103	$72–$134
Opportunity costs
	Median hourly wage for ages 25–54 [27]		34	24–44
	Employment rate ages 25–54 [25]		81.4%	0.73–0.90
	Time lost after surgery		6 weeks	4–36
	Time lost after postoperative complication		6 weeks	4–36
	Time lost after adjuvant radiotherapy		11 weeks	9–26
	Time lost after adjuvant chemotherapy		24 weeks	24–52
Chemotherapy [19,21]
	Chair time		$5,679	$3,975–$7,383
	Adjuvant therapy if high risk disease (6 cycles of paclitaxel and carboplatin)		$16,260	$11,382–$21,138
	Weekly cisplatin (5 cycles if intermediate risk disease)		$1,350	$945–$1,755
Radiotherapy [22,23]
	Adjuvant pelvic radiotherapy		$10,761	$7,533–$13,989
	Brachytherapy		$6,467	$4,527–$8,407
Clinical inputs [15]
	Admission to hospital after surgery
		Radical hysterectomy	0.116	0.10–0.128
		Simple hysterectomy	0.044	0.040–0.048
	Urinary incontinence beyond 4 wk
		Radical hysterectomy	0.11	0.10–0.12
		Simple hysterectomy	0.047	0.042–0.052
	Urinary retention beyond 4 wk
		Radical hysterectomy	0.099	0.090–0.11
		Simple hysterectomy	0.006	0.005–0.007
	3-yr event (recurrence or death)
		Radical hysterectomy	0.022	0.02–0.024
		Simple hysterectomy	0.037	0.033–0.041
Health utility
	Baseline
		Radical hysterectomy	0.83	0.75–0.91
		Simple hysterectomy	0.81	0.73–0.89
	12 mo
		Radical hysterectomy	0.82	0.74–0.90
		Simple hysterectomy	0.80	0.72–0.88
	24 mo
		Radical hysterectomy	0.82	0.74–0.90
		Simple hysterectomy	0.82	0.74–0.90
	36 mo
		Radical hysterectomy	0.82	0.74–0.90
		Simple hysterectomy	0.82	0.74–0.90

CAD, Canadian dollars; CT, computed tomography; MIS, minimally invasive surgery.