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. 2024 Oct 25;12:1447630. doi: 10.3389/fcell.2024.1447630

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Copyright © 2024 Sanovec, Frolikova, Kraus, Vondrakova, Qasemi, Spevakova, Simonik, Moritz, Caswell, Liska, Ded, Cerny, Avidor-Reiss, Hammoud, Schorle, Postlerova, Steger and Komrskova.

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Prediction of Protamine 2/Septin 12 complexes with AlphaFold multimer. The proteins are shown in cartoon representation with Cysteine residues in sticks representation. Residues are color coded according to the transformed pLDDT confidence score using 100-pLDDT with the standard B-factor color scale with cold colors corresponding to high confidence regions. Only residues with pLDDT score higher than 40 are shown. The Protamine 2 moieties are outlined with a grey contour. (A) Predicted complex of mouse Protamine 2 and Septin 12 isoform 1. (B) Predicted complex of mouse Protamine 2 and Septin 12 isoform 3. (C) Predicted complex of human Protamine 2 and Septin 12 isoform 2.