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. 2024 Nov 7;14:27133. doi: 10.1038/s41598-024-78602-0

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

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Fig. 8 — study design of the chronic DSS model. Mice received 3 DSS cycles of which one cycle consists of 1 week of DSS administration followed by 2 weeks of recovery. Twice weekly the mice received intraperitoneal injections of anti-CCR3, isotype or saline. The DAI was determined at those same timepoints. DAI = disease activity index, DSS = dextran sodium sulphate. N = 8 for mice receiving DSS and N = 6 for mice not receiving DSS.