Table 3.
Multiple logistic regression analysis for HAR and AKI in Chinese population and MIMIC-IV database.
| Non-adjusted model | Model 1 | Model 2 | Model 3 | |
|---|---|---|---|---|
| OR (95%Cl), P value | OR (95% Cl), P value | OR (95% Cl), P value | OR (95% Cl), P value | |
| Chinese population | ||||
| HAR, Continuous | 1.24 (1.17–1.32), < 0.001 | 1.21(1.13–1.29), < 0.001 | 1.09 (1.02–1.17), 0.013 | 1.1 (1.02–1.18), 0.016 |
| HAR, Categories | ||||
| Tertile 1 | 1.03 (0.72–1.48), 0.863 | 1.20 (0.83–1.74), 0.337 | 1.31 (0.89–1.93), 0.17 | 1.25 (0.82–1.91),0.297 |
| Tertile 2 | Reference | Reference | Reference | Reference |
| Tertile 3 | 2.06 (1.48–2.85), < 0.001 | 1.93 (1.38–2.69), < 0.001 | 1.45 (1.02–2.05), 0.04 | 1.50 (1.03–2.20), 0.037 |
| P for trend | < 0.001 | 0.003 | 0.464 | 0.275 |
| MIMIC-IV population | ||||
| HAR, Continuous | 1.08 (1.03–1.14), 0.002 | 1.08 (1.02–1.13),0.004 | 1.05 (1.00–1.11), 0.06 | 0.98 (0.92–1.05), 0.649 |
| HAR, Categories | ||||
| Tertile 1 | 1.39 (0.95–2.03), 0.086 | 1.43 (0.98–2.09), 0.065 | 1.57 (1.06–2.32), 0.025 | 1.69 (1.07–2.67), 0.024 |
| Tertile 2 | Reference | Reference | Reference | Reference |
| Tertile 3 | 2.30 (1.58–3.36), < 0.001 | 2.30 (1.57–3.38), < 0.001 | 2.08 (1.39–3.12), < 0.001 | 1.66 (1.03–2.68), 0.038 |
| P for trend | 0.008 | 0.014 | 0.201 | 0.826 |
AKI Acute kidney injury, HAR Hematocrit to ALB ratio, T Tertile, OR Odds ratio, 95%CI 95% Confidence interval.
Results for each model are presented as OR (95% CI), P value.
HAR of Chinese population Tertile 1: < 9.39; Tertile 2: 9.39–10.83; Tertile 3: ≥ 10.83.
Model 1 of Chinese population: adjusted for age and sex.
Model 2 of Chinese population: adjusted for age, sex, hypertension, DM, CHD, HR, RR and SpO2.
Model 3 of Chinese population: adjusted for age, sex, hypertension, DM, CHD, HR, RR, SpO2, etiology, blood transfusion, SOFA score, BISAP score, WBC, and FPG.
HAR of MIMIC-IV database Tertile 1: < 10.13; Tertile 2: 10.13–12.79; Tertile 3: ≥ 12.79.
Model 1 of MIMIC-IV database: adjusted for age and sex.
Model 2 of MIMIC-IV database: adjusted for age, sex, hypertension, DM, CHD, HR, RR and P/F.
Model 3 of MIMIC-IV database: adjusted for age, sex, hypertension, DM, CHD, HR, RR, P/F, blood transfusion, SOFA score, Lac, WBC, and FPG.