Table 2.
Organ donation by donors with death determination by circulatory criteria: logistics and timeline of organ procurement
| Logistic and timeline of organ donation after circulatory death | All (n = 122) | Eligible donors (n = 42) | Ineligible donors (n = 80) | P |
|---|---|---|---|---|
| Duration of ICU or PCU stay, median (IQR) | 7.0 (7.8) | 7.5 (7.8) | 7.0 (6) | 0.613 |
| Respiratory support | 105 (86.1) | 30 (71.4) | 75 (93.8) | 0.206 |
| Endotracheal intubation | 100 (82.0) | 25 (59.5) | 75 (93.8) | 0.050 |
| Tracheostomy | 5 (4.1) | 5 (11.9) | 0 (0.0) | 0.002 |
| Duration of mechanical ventilation support, d, median (IQR) | 7.0 (6.2) | 8.0 (7.1) | 6.3 (6) | 0.086 |
| Antemortem administration of heparin | 118 (96.7) | 42 (100.0) | 76 (95.0) | 0.790 |
| Invasive blood pressure monitoring | ||||
| Yes | 32 (26.2) | 8 (19.0) | 24 (30.0) | 0.261 |
| Unknown | 80 (65.6) | 28 (66.7) | 52 (65.0) | 0.914 |
| Location of WLST | ||||
| Operating room | 79 (64.8) | 24 (57.1) | 55 (68.8) | 0.450 |
| Other | 6 (4.9) | 5 (11.9) | 1 (1.3) | 0.011 |
| Unknown | 37 (30.3) | 13 (31.0) | 24 (30.0) | 0.928 |
| Wisconsin Scale, median (IQR) | 14 (3.0) | 12 (4.8) | 14 (2.0) | 0.186 |
| Distance to centre of organ transplantation, km, median (IQR) | ||||
| Distance to Montreal Heart Institute | 44.0 (224.8) | 14.0 (227.0) | 91.5 (200.2) | 0.664 |
| Distance to Québec Heart and Lung Institute | 241.5 (111.2) | 243 (60.5) | 240.0 (136) | 0.310 |
| Distance to McGill University Health Centre | 43.0 (226.8) | 17.0 (227.5) | 13.0 (200.2) | 0.994 |
| Distance to nearest transplant centre, km, median (IQR) | 13.0 (114.0) | 13.0 (126.0) | 13.0 (114.0) | 0.558 |
| Organs retrieved | ||||
| Kidney | 116 (95.1) | 39 (92.9) | 96.3 (n = 77) | 0.855 |
| Liver | 32 (26.2) | 14 (33.3) | 22.5 (n = 18) | 0.270 |
| Lung | 57 (46.7) | 24 (57.1) | 41.3 (n = 33) | 0.222 |
| Number of organs retrieved per donor | ||||
| Median (IQR) | 2 (1) | 2 (1) | 1 (1) | 0.010 |
| 1 | 58 (47.5) | 16 (38.1) | 42 (52.5) | 0.273 |
| 2 | 45 (36.9) | 17 (40.5) | 28 (35.0) | 0.636 |
| 3 | 19 (15.6) | 9 (21.4) | 10 (12.5) | 0.235 |
| WLST to SBP < 50 mm Hg, min, median (IQR) | 13 (10) | 11.5 (10) | 13.5 (8.75) | 0.408 |
| SBP < 50 mm Hg to asystole, min, median (IQR) | 2 (4.25) | 2.5 (5) | 2 (4) | 0.723 |
| Asystole to skin incision, min, median (IQR) | 5 (1) | 6 (2) | 5 (1) | 0.419 |
| Predicted FWIT duration, min, median (IQR) | 13 (5) | 14 (6.5) | 13 (4) | 0.362 |
Values are n (%), unless otherwise indicated.
FWIT, functional warm ischemic time; ICU, intensive-care unit; IQR, interquartile range; PCU, palliative-care unit; SBP, systolic blood pressure; WLST, withdrawal of life-sustaining therapies.