FIGURE 2.

Locomotor activity and sensorimotor gating property of mice. The traveled distance of mice in an open field was measured. In both genders, no difference was noticed among genotypes (A). The time spent in the peripheral and central regions of the open field was also measured. In both sexes, no difference was noted among the three genotypes (B). The sensorimotor gating property was evaluated by the acoustic startle response. The ratios of prepulse inhibition (PPI) following different prepulse stimuli (68 dB, 71 dB, and 77 dB) were comparable among genotypes in both sexes (C). N = 5 mice in each condition. Results are mean ± SEM.