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| Membrane type | Enzyme payload | Target | Mechanism of action | Reference |
|---|---|---|---|---|
| RBC and macrophage | Uricase | Uric acid | Specific degradation by uricase | (43) |
| RBC | Organophosphorus hydrolase (OPH) | Organophosphate | Specific degradation by OPH | (44) |
| Neuron | N-Sulfotransferase (SxtN) | Saxitoxin (SAX) | Specific binding with membrane ion channel and specific degradation by SxtN | (45) |
