Table 1.
Temperature > 39 °C or <36.5 °C |
Progressive tachycardia > 110 beats per minute (adults) |
Progressive tachypnea > 25 breaths per minute or minute ventilation > 12 L/min (adults) |
Thrombocytopenia < 100,000/µL (does not apply until 3 days after burn) (adults) |
Hyperglycemia in the absence of pre-existing diabetes mellitus |
(Untreated plasma glucose > 200 mg/dL or insulin resistance indicated by >7 units of insulin/h IV drip or >25% increase in insulin requirements over 24 h) |
Inability to continue enteral feedings > 24 h |
(Abdominal distension, enteral feeding intolerance [two times feeding rate in adults], uncontrollable diarrhea [>2500 mL/day]) |
In addition, it is required that a documented infection is identified as follows: |
Culture-positive infection or |
Pathologic tissue source identified or |
Clinical response to antimicrobials |
Based on the 2007 American Burn Association Consensus Conference [19].