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. 2024 Oct 24;13(21):3388. doi: 10.3390/foods13213388

Figure 4.

Figure 4

Impact of zeaxanthin intervention on hepatic glucose metabolism and PI3K/Akt pathway protein expression. The protein expression levels of p-IRS1, IRS1, PI3K, p-Akt, and Akt (A); p-GSK3β, GSK3β, p-GS, and GS (C); p-FOXO1, FOXO1, PEPCK, and G6pase (E); the relative protein levels of p-IRS1, IRS1, PI3K, p-Akt, and Akt (B); p-GSK3β, GSK3β, p-GS, and GS (D); p-FOXO1, FOXO1, PEPCK, and G6pase (F) were analyzed via Western blot analysis. Data are presented as means ± SD (n = 3). ** p < 0.01, and *** p < 0.001 STDZEA, HFD vs. STD; # p < 0.05, ## p < 0.01, and ### p < 0.001 HFDZEA, MET vs. HFD.