Table 3.
Analysis of patient, tumor, treatment aspects, and local recurrence addressing regional referral differences through a comparison of the sarcoma centers.
| Characteristics | Overall (%) | Sarcoma Center Institution 1 (%) |
Sarcoma Center Institution 2 (%) |
p-Value |
|---|---|---|---|---|
| n, (%) | 386 | 158 (40.9) | 228 (59.1) | |
| Female, n (%) | 186 (48.2) | 71 (38. 2/44.9) | 115 (61.8/50.4) | 0.29 |
| Treatment pathway | 0.0001 | |||
| CCP | 297 (76.9) | 105 (35.4/66.5) | 192 (64.6/84.2) | |
| FCP | 89 (23.1) | 53 (59.6/33.5) | 36 (40.4/15.8) | |
| Biological behavior | 0.63 | |||
| Malignant | 286 (74.1) | 115 (40.2/72.8) | 171 (59.8/75.0) | |
| Intermediate | 100 (25.9) | 43 (43.0/27.2) | 57 (57.0/25.0) | |
| Compartment | 0.74 | |||
| DST-S | 317 (82.1) | 131 (41.3/82.9) | 186 (58.6/81.6) | |
| SST-S | 69 (17.9) | 27 (39.1/17.1) | 42 (60.9/18.4) | |
| Initial Size, mm (IQR) | 80 (50–130) | 81 (50–130) | 80 (50–133) | 0.8 |
| Tumor grading | d | a | a | |
| G1 | 138 (36.1) | 62 (44.9/39.2) | 76 (55.1/33.3) | 0.23 |
| G2 | 70 (18.3) | 30 (42.9/19.0) | 40 (57.1/17.5) | 0.72 |
| G3 | 174 (45.6) | 64 (36.8/40.5) | 110 (63.2/48.3) | 0.13 |
| Whoops resections | 96 (24.8) | 41 (42.7/26.0) | 55 (57.3/24.1) | 0.68 |
| Positive resection margins | 148 (39.0) c | 68 (45.9/43.7) b | 80 (54.1/35.6) b | 0.1 |
| Local recurrence n, % | 68 (17.6) | 33 (48.5/20.9) | 35 (51.5/15.3) | 0.0001 |
Data presented in numbers (n) of patients, with percent values in brackets (according to the total overall of the specific variable/according to the sarcoma center institution 1 or 2). Patients are categorized into groups of treatment by sarcoma center 1 or 2. p-values indicate statistical significance of differences between groups, with a threshold of <0.05 considered significant. a two patients not classified; b three patients not classified; c six patients missing; d four patients not classified.