Table 3.
Clinicopathological association of HAO1 protein in breast cancer. Statistically significant p-values shown in bold.
| HAO1 Protein | ||||
|---|---|---|---|---|
| Low n (%) |
High n (%) |
χ2 (p-Value) |
||
| Histological type | ||||
| Ductal carcinoma, No Special Type (NST) | 870 (77) | 261 (23) | ||
| Lobular including Lobular Mixed | 163 (91) | 16 (9) | 19.5 | |
| Metaplastic carcinoma | 6 (86) | 1 (14) | (0.0006) | |
| Other special tumour types | 75 (82) | 16 (18) | ||
| Mixed NST and other special types | 301 (79) | 84 (22) | ||
| Tumour size | ||||
| <2.0 cm | 799 (80) | 198 (20) | 2 | |
| ≥2.0 cm | 616 (77) | 180 (23) | (0.156) | |
| Grade | ||||
| 1 | 226 (81) | 54 (19) | 12.1 | |
| 2 | 569 (83) | 121 (17) | (0.002) | |
| 3 | 620 (75) | 203 (25) | ||
| Lymph Node Stage | ||||
| 1 | 888 (80) | 228 (20) | 0.8 | |
| 2 | 407 (79) | 110 (21) | 0.376 | |
| 3 | 119 (75) | 40 (25) | ||
| Receptor Status | ||||
| ER | + | 1101 (80) | 269 (20) | 8.4 |
| − | 306 (74) | 109 (26) | (0.004) | |
| PR | + | 814 (79) | 213 (21) | 0.3 |
| − | 567 (78) | 158 (22) | (0.6) | |
| HER2 | + | 188 (83) | 40 (17) | 2.1 |
| − | 1191 (78) | 333 (22) | (0.138) | |
| Mitosis | ||||
| 1 | 643 (83) | 131 (17) | 17.2 | |
| 2 | 283 (79) | 76 (21) | (0.0001) | |
| 3 | 489 (74) | 171 (26) | ||
| Pleomorphism | ||||
| 1 | 39 (87) | 6 (13) | ||
| 2 | 520 (83) | 106 (17) | 12.7 | |
| 3 | 856 (76) | 266 (24) | (0.001) | |
| Tubule formation | ||||
| 1 | 103 (82) | 23 (18) | 2.3 | |
| 2 | 411 (77) | 124 (23) | (0.312) | |
| 3 | 901 (80) | 231 (20) | ||
| Nottingham Prognostic Index | ||||
| Good | 484 (82) | 107 (18) | 8 | |
| Moderate | 724 (79) | 197 (21) | (0.018) | |
| Poor | 206 (74) | 74 (26) | ||