Table 1.

Outcomes of various studies reporting the use of DCBs in complex coronary lesions.

References	Population	Outcome with use of DCB	Challenges faced/limitations	Other comments	PMID
Joh et al. [3]	Complex coronary lesions	Comparable risk of Target Vessel Failure between DCB and DES in complex lesions.	Further studies needed to confirm long‐term efficacy of DCB in broader complex lesion populations.	DCB might be a suitable alternative to DES in complex coronary lesions.	39101114
Korjian et al. [4]	Bifurcation	Improved long‐term vessel patency compared to conventional angioplasty; comparable to DES.	Need for further studies to confirm broader applications and efficacy.	DCBs may reduce the necessity for prolonged antiplatelet therapy in high‐risk patients.	38771909
Pan et al. [5]	Ostial lesion	Lower target lesion revascularization (4.90% DCB vs. 16.33% DES); lower MACE rate.	Need for randomized trials to validate findings; potential bias in retrospective design.	Suggests DCB as a viable alternative for managing ostial lesions.	37970224
Lu et al. [6]	Ostial lesion	DCB‐only showed less late lumen loss compared to hybrid strategy; similar safety and efficacy profiles.	Small sample size; need for further validation of findings through larger studies.	DCB‐only may be effective and technically easier than hybrid approaches.	36247262
Felbel et al. [7]	Small‐vessel CAD; Distal vessel segments	Comparable target lesion revascularization rates; lower all‐cause mortality with DCB compared to DES (1% vs. 3%).	Variability in study designs and patient characteristics across included studies; meta‐analysis limitations.	Supports the use of DCB as a promising alternative in managing ostial lesions effectively without stenting.	37671137
Shen et al. [8]	Myocardial Bridges	Successful treatment of atherosclerosis in myocardial bridging; no residual stenosis observed at follow‐up.	Clinical challenges in treating lesions due to physical compression during systole.	Highlights the role of intravascular imaging in assessing myocardial bridging severity	33778455
Zhang et al. [9]	Bifurcation	Similar safety profiles; higher incidence of coronary dissection in DCB group noted, but clinical outcomes comparable to DES.	Increased risk of delayed coronary dissection post‐DCB treatment; limited generalizability due to single‐center study design.	Emphasizes careful monitoring for complications associated with DCB use in bifurcations.	32842271