Figure 2. Hematoxylin and eosin-stained photomicrographs of testicular and ovarian tissue.

Testicular tissue with numerous seminiferous tubules (A, blue stars) lined by a population of germ cells with a typical “fried egg” appearance or abundant, clear cytoplasm and uniform, round nuclei (A, inset, red arrows). These germ cells are supported by Sertoli cells which contain round nuclei and lightly eosinophilic cytoplasm (A, inset, yellow arrows). Ovarian tissue demonstrates ovarian-type stroma composed of numerous spindle cells with storiform architecture (B, green stars). Embedded within the stroma are numerous follicles (B, inset, red arrows) composed of large, round oocytes surrounded by low-cuboidal to flattened follicular cells. Scale bars in each frame are 50μm.