Table 3.
Comparison of the clinical characteristics of the GCAE primary lesion between the metachronous and non-metachronous groups.
| Variables | Metachronous | Univariate Analysis | Multivariate Analysis | ||
|---|---|---|---|---|---|
| (+), 13 Patients, 19 Lesions | (−), 50 Patients, 55 Lesions | p-Value | OR (95% CI) | p-Value | |
| Age (years) | 0.616 | − | − | ||
| <70 | 10 (77) | 35 (70) | |||
| ≥70 | 3 (23) | 15 (30) | |||
| Smoking | 11 (85) | 20 (62) | 0.104 | − | − |
| Gastric cancer family history | 7 (23) | 13 (26) | 0.827 | − | − |
| Eradication period (years) | 0.332 | − | − | ||
| <10 | 11 (85) | 36 (72) | |||
| ≥10 | 2 (15) | 14 (28) | |||
| Gastric mucosal atrophy | 0.012 | 8.53 (1.47–49.4) | 0.016 * | ||
| Mild/moderate | 2 (7) | 27 (54) | |||
| Severe | 11 (93) | 23 (46) | |||
| Tumor size (mm) | 0.235 | − | − | ||
| ≤10 | 3 (16) | 16 (29) | |||
| >10 | 16 (84) | 39 (71) | |||
| Tumor location | 0.261 | − | − | ||
| Upper/middle | 15 (79) | 36 (65) | |||
| Lower | 4 (21) | 19 (35) | |||
| Macroscopic type | 0.12 | − | − | ||
| Superficial elevated | 5 (26) | 6 (11) | |||
| Superficial depressed | 14 (74) | 49 (89) | |||
| Invasion depth | 0.181 | − | − | ||
| Mucosal | 16 (84) | 52 (95) | |||
| Submucosal | 3 (3) | 3 (5) | |||
| Synchronous tumor | 0.439 | − | − | ||
| Negative | 9 (70) | 44 (81) | |||
| Positive | 4 (30) | 10 (19) | |||
| Serum gastrin (pg/mL) | <0.01 * | 8.31 (1.89–36.4) | <0.01 * | ||
| <99 | 5 (38) | 40 (80) | |||
| ≥99 | 8 (62) | 10 (20) | |||
| Serum PG I (ng/mL) | <0.01 * | − | − | ||
| <19.8 | 4 (31) | 0 (0) | |||
| ≥19.8 | 9 (69) | 50 (100) | |||
| Serum PG II (ng/mL) | 0.622 | − | − | ||
| <10.7 | 9 (69) | 38 (76) | |||
| ≥10.7 | 4 (31) | 12 (24) | |||
| PG I/II ratio | <0.01 * | − | − | ||
| <4.6 | 9 (69) | 14 (28) | |||
| ≥4.6 | 4 (31) | 36 (72) | |||
(%) GCAE, gastric cancer after eradication; CI, confidence interval; OR, odds ratio. *: a significant difference.