Table 5.

Results obtained in the follow up period after treatment discontinuation.

Ref.	Follow-Up Duration	Findings During Follow-Up
[88]	2 weeks	Abnormal stool frequency continued to improve significantly in the active group after the discontinuation of supplementation.
[98]	2 weeks	After the follow-up period, significant differences were no longer detected in both groups in terms of improvement in the severity of symptoms, but the total number of days with pain was only reduced in the active group.
[81]	2 weeks	After discontinuation of supplementation, the values for the probiotic species found in feces decreased, suggesting that treatment effects were transient.
[78]	3 weeks	The improvements obtained continued to be observed in the follow-up period.
[112]	1 month	The improvements obtained continued to be observed in the follow-up period.
[101]	1 month	The response to probiotics remained after treatment discontinuation, although there was increase of the clinical response in the placebo group, resulting in disappearance of the previously observed significant differences.
[80]	1 month	There was a maintenance of the effects obtained during the treatment.
[108]	1 month	There was a maintenance of the effects obtained during the treatment.
[85]	2 months	After follow-up, no significant differences previously observed between groups remained.
[115]	1 year	The trial was carried out with 1 year of follow-up using a web application, and whenever there was symptomatic worsening, patients performed a cycle of treatments for 4 weeks, and improvements in symptomatology were observed among them.