Table 3.
Work productivity and activity impairment in the past seven days as assessed by WPAI:GH in the overall M2S-AD population and by EASI-based AD severity.
| Overall (N = 184) |
m-AD (N = 117) |
s-AD (N = 67) |
||
|---|---|---|---|---|
| All patients | ||||
| Employed, n | 112 | 72 | 40 | |
| Absenteeism | Completion rate, % (n/N) | 97.3 (109/112) | 95.8 (69/72) | 100.0 (40/40) |
| Mean (SD) score, % | 4.9 (12.0) | 4.9 (14.1) | 4.7 (7.2) | |
| Median (IQR) score, % | 0.0 (0.0–4.8) | 0.0 (0.0–2.0) | 0.0 (0.0–6.0) | |
| Presenteeism | Completion rate, % (n/N) | 99.1 (111/112) | 98.6 (71/72) | 100.0 (40/40) |
| Mean (SD) score, % | 27.1 (26.3) | 25.8 (27.0) | 29.5 (25.3) | |
| Median (IQR) score, % | 20.0 (0.0–40.0) | 20.0 (0.0–40.0) | 20.0 (10.0–45.0) | |
| Work productivity loss | Completion rate, % (n/N) | 97.3 (109/112) | 95.8 (69/72) | 100.0 (40/40) |
| Mean (SD) score, % | 29.8 (27.3) | 28.0 (28.5) | 32.8 (25.2) | |
| Median (IQR) score, % | 23.8 (2.4–50.0) | 20.0 (0.0–46.6) | 26.9 (10.0–51.0) | |
| Activity impairment | Completion rate, % (n/N) | 100.0 (184/184) | 100.0 (117/117) | 100.0 (67/67) |
| Mean (SD) score, % | 34.2 (30.0) | 29.5 (28.6) | 42.4 (30.7) | |
| Median (IQR) score, % | 30.0 (5.0–60.0) | 20.0 (0.0–50.0) | 40.0 (20.0–70.0) | |
| Patients reporting any work productivity loss/activity impairment | ||||
| Absenteeism | Patients reporting absenteeism, % (n/N) | 34.9 (38/109) | 27.5 (19/69) | 47.5 (19/40) |
| Mean (SD) score, % | 13.9 (17.1) | 17.9 (22.5) | 9.9 (7.6) | |
| Median (IQR) score, % | 7.0 (4.8–21.1) | 11.1 (4.0–23.7) | 6.5 (4.8–14.3) | |
| Presenteeism | Patients reporting presenteeism, % (n/N) | 71.2 (79/111) | 66.2 (47/71) | 80.0 (32/40) |
| Mean (SD) score, % | 38.1 (23.5) | 38.9 (24.2) | 36.9 (22.9) | |
| Median (IQR) score, % | 30.0 (20.0–60.0) | 30.0 (20.0–60.0) | 30.0 (20.0–55.0) | |
| Work productivity loss | Patients reporting work productivity loss, % (n/N) | 75.2 (82/109) | 69.6 (48/69) | 85.0 (34/40) |
| Mean (SD) score, % | 39.6 (24.5) | 40.3 (25.9) | 38.6 (22.7) | |
| Median (IQR) score, % | 33.3 (20.0–60.0) | 34.1 (20.0–60.0) | 31.7 (22.0–55.6) | |
| Activity impairment | Patients reporting activity impairment, % (n/N) | 75.0 (138/184) | 70.9 (83/117) | 82.1 (55/67) |
| Mean (SD) score, % | 45.6 (26.0) | 41.6 (25.5) | 51.6 (25.8) | |
| Median (IQR) score, % | 40.0 (20.0–70.0) | 40.0 (20.0–60.0) | 50.0 (30.0–70.0) | |
Abbreviations: AD, atopic dermatitis; EASI, Eczema Area and Severity Index; IQR, interquartile range; M2S, moderate-to-severe; m-AD, moderate AD; n, number of patients with variable; N, number of patients with available data; s-AD, severe/very severe AD; SD, standard deviation; WPAI:GH, Work Productivity and Activity Impairment: General Health (questionnaire).