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. 2024 Oct 29;13(21):6477. doi: 10.3390/jcm13216477

Table 1.

Clinical practice guidelines for management of pregnancy in persons with primary immune thrombocytopenia.

Recommended Management Strength of
Recommendation
Society
During Pregnancy
  • Platelet count <30 × 109/L or symptomatic bleeding causes the pregnant patient to receive either corticosteroids or intravenous immune globulin (IVIg)

Strong
recommendation
American Society of
Hematology [8]
  • Treatment should be initiated if platelet count <30 × 109/L, or if there is symptomatic bleeding, or to increase platelet counts to a level considered safe for procedures

Conditional
suggestion
American College of Obstetricians and Gynecologists [10]
During or for Delivery
  • Mode of delivery (vaginal vs. cesarean section) should be based on obstetric concerns (platelet count threshold not indicated)

Conditional
suggestion
American Society of
Hematology [8]
  • Treatment should be initiated for platelet counts <50 × 109/L for a cesarean delivery

Conditional
suggestion
American College of Obstetricians and Gynecologists [10]
  • Treatment should be initiated for platelet counts <70 × 109/L for an epidural placement

Conditional
suggestion
American College of Obstetricians and Gynecologists [10]