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Cholesterol level was restored in NPC1-knocked out CHO (CT43) cells upon treatment with Rosa canina methanol extract (RCME). The wild-type Chinese hamster ovary (CHO-WT) cells and NPC1-knocked out CHO (CT43) cells were treated for 24 h with RCME. After cholesterol extraction, the measurement was performed with HPLC. Ordinary one-way ANOVA, ns p > 0.05, * p < 0.05 versus untreated group, S.E.M., and n = 3.
