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(a) Molecular interactions and binding pose of compound 3d at the interface of human tryptase with potent non-peptide inhibitor (PDB: 2ZA5); H bonds between the macromolecule and compound 3d are shown as yellow dashes and distances are in Å units; (b) Connelly surface of docking pose of 2ZA5 with 3d shown as stick model; (c) receptor surface: H-bond donor vs. acceptor ability of surrounding amino acids; (d) 2D interaction map between 2ZA5 and 3d.
