Table 1.

Influence of reaction parameters on the biocatalytic synthesis of hydroxytyrosyl hexanoate by esterification of Hex with HT (0.25 mmol) in 70% (w/w) [C₁₂mim][NTf₂] reaction medium. Yield (ε) and productivity (mmol HT-Hex/g N435 h) have been calculated at 3 h reaction time.

Entry	HT:Hex (mol: mol)	N435/HT (mg/mmol)	T (°C)	ε (%)	Productivity (mmol HT-Hex/g N435 h)
1	1:4	50	80	33	2.2
2	1:4	100	80	83	2.8
3	1:4	200	80	81	1.4
4	1:4	400	80	87	0.7
5	1:4	100	70	71	2.4
6	1:4	100	60	47	1.6
7 a	1:2	100	80	78	2.6

^a 0.5 mmol HT.