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. 2024 Oct 30;16(21):3720. doi: 10.3390/nu16213720

Table 5.

Association between thyroid nodules, iodine nutritional status, and associated factors in participants with and without positive thyroid antibodies.

   Thyroid Nodules
 TPOAb (−)/TgAb (−)  TPOAb (+) or TgAb (+)
OR (95% CI) p OR (95% CI) p
BMI 1.005 (0.981, 1.029) 0.707 1.086 (0.914, 1.291) 0.349
Ages
 6–8 Reference Reference
 9–11 0.843 (0.677, 1.049) 0.126 0.947 (0.205, 4.376) 0.945
 12–17 0.428 (0.325, 0.564) <0.001 0.585 (0.087, 3.946) 0.582
Sex
 Male
 Female 0.780 (0.662, 0.920) 0.003 0.721 (0.207, 2.510) 0.607
Region
 Urban
 Rural 1.512 (1.267, 1.804) <0.001 1.018 (0.305, 3.405) 0.976
UIC, µg/L
 <100 0.879 (0.683, 1.130) 0.314 0.413 (0.099, 1.731) 0.227
 100–199.9
 200–299.9 0.805 (0.645, 1.005) 0.055 0.640 (0.167, 2.451) 0.515
 ≥300 0.878 (0.692, 1.113) 0.281 1.543 (0.297, 8.010) 0.606
UI/Cr, µg/g
 <111.5 (Quartile 1) 1.088 (0.878, 1.348) 0.441 1.345 (0.380, 4.756) 0.646
 111.5–241.8 (Quartile 2 + Quartile 3)
 >241.8 (Quartile 4) 1.197 (0.962, 1.489) 0.107 0.506 (0.123, 2.076) 0.344

Bold remarks indicate statistically significant differences. Abbreviations: OR: odds ratio; 95% CI: 95% confidence interval; BMI, body mass index; UIC, urinary iodine concentration; UI/Cr, urinary iodine-to-creatinine ratio; TgAb, thyroglobulin antibody; TPOAb, thyroid peroxidase antibody.