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Effect of P72 on IS-induced DA- and insomnia-like behaviors in mice. Effect of P72 on TD (a), DC (b), TC (c), and travel pathway (d) in OFT. Effect on OT (e) and OE (f) in the EPMT and IT in TST (g). Effect on SLT (h) and SLD (i). IS, saline; P72, 1 × 109 CFU/mouse/day of P72 in IS/IF-treated mice; NC, saline in mice (not exposed IS/IF). Data values indicate mean ± SD (n = 8). # p < 0.05 vs. NC. * p < 0.05 vs. IS.
