Table 1.
Summary of QC results in cell pellets for metformin.
| LLOQ 0.05 ng/mL |
QC A 0.15 ng/mL |
QC B 18.7 ng/mL |
QC C 37.5 ng/mL |
|
|---|---|---|---|---|
| Intra-day | ||||
| 1 Mean [ng/mL] | 0.0536 | 0.141 | 16.7 | 32.0 |
| Accuracy (%) | 107 | 93.9 | 89.0 | 85.4 |
| Precision (% CV) | 9.97 | 3.49 | 3.09 | 3.85 |
| 2 Mean [ng/mL] | 0.0471 | 0.132 | 16.8 | 34.0 |
| Accuracy (%) | 94.2 | 88.3 | 89.4 | 90.7 |
| Precision (% CV) | 9.60 | 3.04 | 3.24 | 4.11 |
| 3 Mean [ng/mL]) | 0.0498 | 0.142 | 16.8 | 33.3 |
| Accuracy (%) | 99.7 | 95.0 | 89.6 | 88.9 |
| Precision (% CV) | 8.28 | 6.47 | 5.36 | 2.94 |
| Inter-day | ||||
| Mean [ng/mL] | 0.0512 | 0.139 | 16.8 | 33.3 |
| Accuracy (%) | 102 | 92.7 | 89.4 | 88.9 |
| Precision (% CV) | 11.2 | 5.40 | 3.87 | 3.22 |
n = 6; CV—coefficient of variation; LLOQ—lower limit of quantification; QC—quality control.