Table 1.
Examples of commercial drugs based on osmotic pumps.
| Drug | Active Ingredient | Application | Ref. |
|---|---|---|---|
| Actoplus Met XR (Takeda Pharmaceuticals Company, Tokyo, Japan) | Pioglitazone and metformin hydrochloride |
Glycaemic control in adults with type 2 diabetes mellitus | [42] |
| Adalat Oros (Bayer, Leverkusen, Germany) |
Nifedipine | Angina and hypertension | [43] |
| Concerta®
(Janssen Pharmaceuticals, Inc., Beerse, Belgium) |
Methylphenidate hydrochloride |
Attention deficit hyperactivity disorder | [44] |
| Ditropan XL®
(Janssen Pharmaceuticals, Inc., Beerse, Belgium) |
Oxybutynin chloride | Overactive bladder | [45] |
| Elafax® XR (Gador S.A., Bueno Aires, Argentina) |
Venlafaxine | Major depressive disorder, generalized anxiety disorder, and panic disorder | [46] |
| Glucotrol XL (Pfizer, Inc., New York, NY, USA) |
Glipizide | Improve glycaemic control in patients with type 2 diabetes mellitus | [47] |
| Osmolex ERTM (Supernus Pharmaceuticals, Rockville, MD, USA) |
Amantadine hydrochloride |
Parkinson’s disease and drug-induced extrapyramidal reactions in adults |
[48] |
| Procardia XL® (Pfizer, Inc., New York, NY, USA) |
Nifedipine | Angina and hypertension | [49] |