TABLE 4.

Regression Estimates of the Associations of PHQ-2 Scores With Measures of Well-Being and Functioning

	Baseline associations (cross-sectional)				Associations between PHQ-2 mean change and mean change in outcomes (longitudinal)
Outcome*
Well-being	Beta	95% CI	P	r † (model/PHQ-2)	Beta	95% CI	P	r † (model/PHQ-2)
Life satisfaction (0‒10)	−0.26	−0.32, −0.21	<0.001	0.13/0.03	−0.01	−0.10, 0.07	0.808	0.01/0.00
Purpose in life (6‒30)	−0.77	−0.91, −0.64	<0.001	0.14/0.04	−0.19	−0.34, −0.04	0.013	0.02/0.01
Social health (1–5)	−0.09	−0.13, −0.06	<0.001	0.14/0.01	0.03	−0.01, 0.06	0.147	0.01/0.00
Functioning
PEG Pain (0–10)	0.16	0.10, 0.23	<0.001	0.17/0.01	0.03	−0.05, 0.12	0.449	0.01/0.00
PROMIS Physical Health Functioning‡	−0.82	−1.02, −0.61	<0.001	0.19/0.02	−0.12	−0.32, 0.09	0.268	0.01/0.00
PROMIS Mental Health Functioning‡	−1.75	−1.99, −1.50	<0.001	0.27/0.07	−0.29	−0.54, −0.04	0.022	0.02/0.01
Perceived Stress (4‒20)	0.53	0.43, 0.62	<0.001	0.17/0.04	0.13	0.02, 0.24	0.026	0.02/0.00

^* Numbers in parentheses indicate the minimum to a maximum range of scale scores, with bolded numbers indicating the worst score.

^† Confidence interval.

^‡ For PROMIS scales, 50 represents the population norm, with lower scores indicating worse functioning and 10 representing 1 SD.

PHQ-2 indicates Patient Health Questionnaire-2.