Table 1. Descriptions of studies on participants with peripheral neuropathic pain.
| Study | Design | Country | Study population | Techniques | Intervention and comparator | Outcomes measured |
|---|---|---|---|---|---|---|
| Pinar 2005 [45] | RCT | Turkey | CTS (n = 26) | Tension | Splint plus patient training program or splint plus patient training program plus neural mobilisation | Before and 10-week after intervention • NCS (electrophysiologic test): distal motor latency |
| Baysal et al. 2006 [7] | RCT | Turkey | CTS (n = 36) | Tension | Splinting plus neural mobilisation or splinting plus ultrasound or splinting plus neural mobilisation plus ultrasound | Before, after intervention, and 8-week after intervention • NCS: motor latency, sensory latency |
| Bialosky et al. 2009 [47] | RCT | United States | CTS (n = 40) | Tension | Neural mobilisation or sham technique | Before and after intervention • NCS (electrodiagnostic test): distal motor latency |
| Svernlöv et al. 2009 [48] | RCT | Sweden | Cubital Tunnel Syndrome n = 70 (n = 39 women and n = 31 men) |
Tension | Splinting plus information or neural mobilisation plus information or information | Before and 6-month after intervention • NCS: sensory conduction velocity, motor conduction velocity, electromyography |
| Schmid et al. 2012 [23] | RCT | Australia | CTS (n = 20) | Sliding | Splinting or neural mobilisation home program | Before, 10-minute after intervention, and 1-week after intervention • Nerve structure evaluation: signal intensity |
| Oskouei et al. 2014 [54] | RCT | Iran | CTS n = 20 (n = 16 hands in each group) | Tension | Routine physiotherapy (splint, TENS, and therapeutic ultrasound) or routine physiotherapy plus neural mobilisation | Before and 4-week after intervention • NCS: motor distal latency and sensory distal latency |
| Ginanneschi et al. 2015 [42] | QES | Italy | CTS n = 16 [n = 8 hands (men = 1; women = 7) and 8 healthy participants] |
Tension | Neural mobilisation | Before and after intervention • NCS: sensory conduction velocity, sensory action potential amplitude, distal motor latencies |
| Wolny et al. 2017 [49] | RCT | Poland | CTS (n = 140) | Sliding and tension | Neural mobilisation plus functional massage plus bone mobilisations techniques or laser plus ultrasound therapy | Before and after intervention • NCS: sensory conduction velocity, motor conduction velocity, motor latency, standardized latency |
| Yildirim et al. 2018 [46] | RCT | Turkey | CTS (n = 21) | Tension | Kinesiotaping plus neural mobilisation or neural mobilisation | Before, 3-week after intervention, and 6-week after intervention • Nerve structure evaluation: CSA |
| Wolny & Linek, 2018 [50] | RCT | Poland | CTS (n = 150) | Sliding and tension | Neural mobilisation or “sham” therapy | Before and after intervention • NCS: sensory conduction velocity, motor conduction velocity, motor latency |
| Neto et al. 2019 [43] | QES | Portugal | Sciatica n = 16 (n = 8 chronic sciatica and n = 8 health participants) | Tension | Neural mobilisation | Before and after intervention • Nerve structure evaluation: nerve stiffness (SWV) |
| Wolny & Linek, 2019 [51] | RCT | Poland | CTS (n = 103) | Sliding and tension | Neural mobilisation or control group | NCS: Before and 1-month after treatment • NCS: sensory conduction velocity, motor conduction velocity, motor latency |
| Paquette et al. 2020 [44] | QES | Canada | CTS (n = 14) | Sliding | Neural mobilisation home program plus videoconference plus logbook | Before and 1-week after the completion of a 4-week intervention program • NCS (US): nerve biological integrity, nerve mechanical properties |
| Talebi et al. 2020 [52] | RCT | Iran | CTS (n = 30) | Tension | Nerve mobilisation or mechanical interface mobilisation | Before and immediately after the end of the treatment period • NCS: motor distal latency, sensory distal latency |
| Khademi et al. 2023 [53] | QES | Iran | CTS (n = 20) | Tension | Neural mobilisation | Before and immediately after one session of neural mobilisation • Nerve structure evaluation: nerve stiffness • Nerve structure evaluation: CSA |
Abbreviations: CSA = Cross-Sectional Area; CTS = Carpal Tunnel Syndrome; NCS = Nerve Conduction Studies; QES = Quasi-Experimental Study
RCT = Randomised Clinical Trials; SWV: Shear Wave Velocity; TENS = Transcutaneous Electrical Nerve Stimulation.