Table 3.
The effects of 2 days of MeAIB (5 mm, icv) administration on PN0–1 compared to PN5–6 on the expression of feminizing or aggressive behaviors in hormone-primed castrated male rats
| Age, days | PN0–1 | PN5–6 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Behavior | LQ, % | LS | lordosis, n | confrontation to mounting, % | mount attempts, n | immobility, s | LQ, % | LS | lordosis, n | confrontation to mounting, % | mount attempts, n | immobility, s |
| Pretreatment | ||||||||||||
| DW | 0±0 (3) | 0±0 (3) | 0±0 (3) | 60±21 (3) | 2.44±1.68 (3) | 18.9±17.2 (3) | 3.3±3.3 (5) | 0.04 ±0.04 (5) | 0.33±0.33 (5) | 47±17 (5) | 8.67±3.27 (5) | 327.7±305.0 (5) |
| MeAIB | 0±0 (3) | 0±0 (3) | 0±0 (3) | 68±16 (3) | 8.56± 1.44 (3)a | 0±0 (3) | 1.3±0.8 (5) | 0.03 ±0.02 (5) | 0.2±0.13 (5) | 18±9 (5) | 5.47±2.09 (5) | 151.7±149.6 (5) |
There were no significant differences in the results between the two age groups.
icv, intracerebroventricular injection; PN, postnatal day; LQ, lordosis quotient; LS, lordosis score; DW, distilled water.
p = 0.67, p = 0.74, p = 0.78, p = 0.29, p = 0.11, and p = 0.73 for LQ, LS, total number of lordosis, percentage of confrontation to mounting, mount attempts, and immobility, respectively; two-way ANOVA (age × pretreatment).
The numbers in parentheses indicate the number of animals tested.
a p = 0.052, compared with the DW-pretreated (control) group, unpaired t test.