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. Author manuscript; available in PMC: 2024 Nov 8.
Published in final edited form as: Synapse. 2019 Jan 22;73(5):e22088. doi: 10.1002/syn.22088

Fig. 3. LEnk levels in CA3 are modestly reduced in Oxy-CIS females.

Fig. 3.

A. Low magnification photomicrograph of the rat dorsal hippocampus shows LEnk-ir in the mossy fiber pathway within stratum lucidum (SLu) of CA3a, b and c and in the crest (cr), central hilus (ch), and dorsal blade (db) of the dentate gyrus (DG). B. High magnification photomicrographs show higher levels of LEnk-ir in CA3c SLu in a Sal-CIS female rat compared to an Oxy-CIS female rat. C. Oxy-CIS females compared to Sal-CIS females demonstrate decreased levels of LEnk-ir in the CA3c and a trend towards decreased levels of LEnk-ir in the CA3a. Oxy-CIS males compared to Sal-CIS males show no difference in levels of LEnk-ir in the CA3. D. Oxy-CIS females and males compared to Sal-CIS females and males show no difference in levels of LEnk-ir in any subregion of the DG. *p ≤ 0.05; ^p = 0.069; N = 6 rats per group. Scale bars: A = 500 μm; B = 100 μm