A,B. There are no differences in plasmalemmal or near plasmalemmal DOR-SIG particle density in CA3 dendrites between Sal- and Oxy-CIS females and males. C,D. Sal-CIS females have a significantly lower density of DOR-SIG particles in the cytoplasm and in total in CA3 pyramidal cell dendrites compared to Sal-CIS males. SF, Sal-female; SM, Sal-male; OF, Oxy-female; OM, Oxy-male. **p < 0.01, *p ≤ 0.05; N = 3 rats per group; n = 50 dendrites per rat.