Table 2.

Management of hypercortisolism and Cushing’s syndrome

All Centres (n = 82)
(6) In which group of patients, you request the evaluation of 24 h urinary free cortisol or the overnight 1-mg dexamethasone suppression test if not performed before?
(a) Patients with hypertension and specific features (buffalo hump, moon facies, purple reddish striae)	63 (76.8)
(b) All patients with diabetes and hypertension	6 (7.3)
(c) All patients with hypertension and adrenal mass	55 (65.9)
(d) All patients with hypertension and obesity	9 (11.0)
(e) All patients with hypertension and obesity and adrenal mass	31 (37.8)
(f) All patients with resistant hypertension	50 (61.0)
(g) All patients with hypertension aged less than 50 years	26 (31.7)
(h) When the phenotype is suspect, I refer the patient to an endocrinologist	13 (15.9)
(7) Which test(s) do you perform for screening of hypercortisolism?
(a) 1-mg overnight dexamethasone suppression test	40 (48.8)
(b) 24 h urinary free cortisol	54 (65.9)
(c) Late night salivary cortisol	9 (11.0)
(d) Basal cortisol and ACTH	44 (53.7)
(e) Adrenal CT scanning or MRI	10 (12.2)
(f) I refer to the endocrinologist without performance of any test	10 (12.2)
(8) Are you aware of a referral centre in your area with expertise of Cushing syndrome management?
(a) Yes	57 (69.5)
(b) No	25 (30.5)
(9) How do you consider a patient with a level of cortisol of 2.5 μg/dL at 8 a.m. after overnight 1-mg dexamethasone suppression test?
(a) Positive	12 (14.6)
(b) Negative	4 (4.9)
(c) Grey zone, I request further tests	33 (40.2)
(d) I refer to an endocrinologist	33 (40.2)

Responses to questions 6-to-9 of the questionnaire. Data are reported as absolute numbers and frequencies, as appropriate