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. 2024 Jul 24;48:130. doi: 10.11604/pamj.2024.48.130.40509

Table 2.

univariate analytical study of prognostic factors

Prognostic factors Group with and without prognostic factor Alive Dead P value
Type of IFI* IA:14 7 7 0.573
Fongemia:13 7 6
Sex Male:14 6 8 0.043
Female:15 9 6
Age <65 years: 28 15 13 0.19
≥65 years: 1 0 1
Hemopathy AML: 16 9 7 0.265
ALL: 6 4 2
Lymphoma: 3 1 2
Medullary aplasia: 3 0 3
Multiple myeloma: 1 1 0
Disease status Complete remission: 6 4 2 0.038
Partial remission: 3 3 0
Relapse/progression: 12 3 9
Active disease: 8 5 3
Neutropenia Yes: 27 13 14 0.259
No: 2 2 0
Depth of neutropenia <500: 16 7 9 0.358
500-1000: 1 1 0
>1000: 1 0 1
Duration of neutropenia ≥3 weeks: Yes: 9 2 7 0.041
No: 9 6 3
Broad-spectrum Antibiotic therapy Yes: 17 8 9 0.5
No: 9 5 4
Parenteral nutrition Yes: 12 5 7 0.297
No: 17 10 7
Corticosteroid therapy Yes: 8 6 2 0.155
No: 20 9 11
Renal failure Yes: 4 15 10 0.042
No: 25 0 4
Extended stay in the hematology department Yes: 20 9 11 0.25
No: 9 6 3
Central venous catheter Yes: 11 6 5 0.558
No: 18 9 9
Prophylactic antifungal treatment Yes: 9 3 6 0.048
No: 17 10 7
Time to start antifungal treatment (days) Average for living: 0.67 15 - 0.016
Average among decedents: 2.07 - 14
Thrombocytopenia Yes: 22 11 11 0.4
No: 6 4 2
Lactate level (mmol/l) Average for living: 1.67 10 - 0.035
Average among decedents:3.14 - 14
Procalcitonin level (ng/ml) Average for living:5.30 10 - 0.043
Average among decedents:7.79 - 13
Fibrinogen level (g/l) Average for living:3.46 8 - 0.048
Average among decedents:4.23 - 11
*

For the type of IFIs, neuromeningeal cryptococcosis and pulmonary mucormycosis were excluded from the list to avoid biasing the calculation.