Table 3.
Time trend in aAARs of GB over the period 1993–2017 by sex (Standard: Europe 2013).
| Period | Male | Female | Both sexes | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No. | CR | AAR | 95%CI | No. | CR | AAR | 95%CI | No. | CR | AAR | 95%CI | |
| 1993–1995 | 28 | 2.12 | 2.64 | 1.54–3.75 | 23 | 1.55 | 1.63 | 0.96–2.31 | 51 | 1.82 | 2.02 | 1.45–2.59 |
| 1996–1998 | 41 | 3.19 | 3.91 | 2.60–5.22 | 30 | 2.08 | 2.13 | 1.36–2.90 | 71 | 2.60 | 2.85 | 2.17–3.53 |
| 1999–2001 | 45 | 3.59 | 4.07 | 2.81–5.33 | 33 | 2.34 | 2.32 | 1.53–3.11 | 78 | 2.92 | 3.07 | 2.38–3.76 |
| 2002–2004 | 47 | 3.81 | 4.31 | 3.03–5.59 | 38 | 2.73 | 2.77 | 1.87–3.66 | 85 | 3.24 | 3.46 | 2.71–4.21 |
| 2005–2007 | 47 | 3.80 | 4.32 | 3.03–5.61 | 39 | 2.81 | 2.89 | 1.98–3.80 | 86 | 3.28 | 3.52 | 2.76–4.28 |
| 2008–2010 | 55 | 4.48 | 4.91 | 3.59–6.23 | 43 | 3.11 | 3.15 | 2.21–4.10 | 98 | 3.76 | 4.00 | 3.20–4.79 |
| 2011–2013 | 52 | 4.24 | 4.41 | 3.20–5.63 | 37 | 2.69 | 2.72 | 1.84–3.61 | 89 | 3.42 | 3.53 | 2.79–4.26 |
| 2014–2017 | 65 | 4.04 | 4.23 | 3.19–5.28 | 44 | 2.45 | 2.46 | 1.73–3.20 | 109 | 3.20 | 3.30 | 2.67–3.92 |
| Total | 380 | 3.65 | - | - | 287 | 2.46 | - | - | 667 | 3.02 | - | - |
| 3YMPV | - | - | 4.2 | –0.9/9.5 | - | - | 5.1 | –1.2/11.9 | - | - | 5.3 | –0.4/11.3 |
aAAR, age-adjusted incidence rate per 100,000 person-years (standard: Europe 2013); GB, glioblastoma; CI, confidence intervals; CR, crude incidence rate per 100,000 person-years; No., observed incident cases; 3YMPV, 3-year mean percent variation.