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. 2024 Nov 8;7:1467. doi: 10.1038/s42003-024-07017-4

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — High-magnification views of the rectangles (a–f) demarcated in Fig. 3. a The respiratory mucosa consists of respiratory epithelium and lamina propria separated by a basal lamina (dashed line). Dark spaces reflect goblet cells (arrowheads). The faint signal for OMP near the middle of the image is an artifact produced by a tissue fold. b The olfactory mucosa consists of olfactory epithelium and lamina propria separated by a basal lamina (dashed line). The olfactory epithelium contains immature OSNs (arrows) and mature, OMP-immunoreactive OSNs (arrowheads). c Olfactory axon fascicles, formed by OSN axons within the lamina propria, appear as longitudinal or oblique sectional views (arrows) or as a cross-sectional view (arrowhead). d Glomeruli (arrows) are innervated by axons of OSNs (double arrows). Most glomeruli reside within the glomerular layer (dashed vertical line). Some invasive glomeruli with an elongated appearance (arrowhead) reside deeper, within the external plexiform layer (solid vertical line). e Arterial vasculature is identified by an internal elastic lamina (arrowhead) and a surrounding layer of elongated nuclei of smooth muscle cells (I-beam line) that are parallel to the internal elastic lamina and surround a luminal space (asterisk). The diamond indicates a vein. f Bone (dotted line) is acellular, has a laminar appearance (arrowhead), and is not fluorescently stained.