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. 2024 Oct 1;9(10):103664. doi: 10.1016/j.esmoop.2024.103664

Figure 2.

Figure 2

Management of local or locoregional GUGy-NENs. Purple: algorithm title; orange, surgery; dark green: RT; blue: systemic anticancer therapy or their combination; turquoise: non-systemic anticancer therapies or combination of treatment modalities; white: other aspects of management and non-treatment aspects. ChT, chemotherapy; CPG, Clinical Practice Guideline; CRT, chemoradiotherapy; G, grade; GUGy, genitourinary or gynaecological; NEC, neuroendocrine carcinoma; NEN, neuroendocrine neoplasm; NET, neuroendocrine tumour; R1, resection with microscopic tumour at the margin; R2, resection with macroscopic tumour at the margin; RT, radiotherapy. aFour cycles of platinum–etoposide.