Figure 7.

Management of ITC. Purple: algorithm title; orange: surgery; dark green: RT; blue: systemic anticancer therapy or their combination; turquoise: non-systemic anticancer therapies or combination of treatment modalities; white: other aspects of management and non-treatment aspects. ChT, chemotherapy; CPG, clinical practice guideline; CRT, chemoradiotherapy; ITC, intrathyroid thymic carcinoma; MTB, multidisciplinary tumour board; RT, radiotherapy. ^aIn selected cases after careful MTB discussion. ^bAdjuvant RT may be discussed for patients who have not received prior RT [V, B]. ^cCisplatin-based regimens with either doxorubicin and cyclophosphamide or etoposide.