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. 2024 Nov 5;17:4853–4863. doi: 10.2147/IDR.S491379

Table 3.

Demographic, Clinical Characteristics of PNM Cases and Univariate Analysis

Variable All Patients (900) Non-Survivors(112) Survivors(788) P
Basic condition
 Gender 516(57.3%) 70(62.5%) 446(56.6%) 0.262
 Age 41(27,54) 41(27,53) 47(31,58) 0.157
Original disease
 Cranial tumors 603(67.0%) 73(65.2%) 530(67.3%) 0.668
 Spinal tumors 18(2.0%) 1(0.9%) 17(2.2%) 0.715
 Functional neurosurgery 48(5.3%) 2(1.8%) 46(5.8%) 0.111
 Neurovascular surgery 58(6.4%) 8(7.1%) 50(6.3%) 0.840
 Craniocerebral trauma surgery 53(5.9%) 7(6.3%) 46(5.8%) 0.830
 Others 120(13.3%) 21(18.8%) 99(12.6%) 0.076
Risk factors
 Diabetes 33(3.7%) 5(4.4%) 28(3.6%) 0.592
 Hypertension 141(15.7%) 33(29.5%) 108(13.7%) <0.001
 TEM(°C) 37.6±0.9 37.8±0.9 37.6±0.9 0.025
 Tumor 621(69.0%) 80(71.4%) 541(68.7%) 0.587
 Malignant tumor 282(31.3%) 48(42.9%) 234(29.7%) 0.007
 Length of operation(hours) 4.5±3.0 5.0±3.0 4.5±3.0 0.062
 Reoperation 199(22.1%) 39(34.8%) 160(20.3%)) 0.001
 Craniotomy 625(69.4%) 79(70.5%) 546(69.3%) 0.872
 Surgical site 0.715
 Head 882(98.0%) 111(99.1%) 771(97.8%)
 Spine 18(2.0%) 1(0.9%) 17(2.2%)
 Type of incision 0.481
 Clean 471(52.3%) 55(49.1%) 416(52.8%)
 Contamination 429(47.7%) 57(50.9%) 372(47.2%)
 ICU admission 357(39.7%) 80(71.4%) 277(35.2%) <0.001
 CSF leakage 138(15.3%) 23(10.5%) 115(14.6%) 0.122
 EVD 362(40.2%) 69(61.6%) 293(37.2%) <0.001
 LD 257(28.6%) 48(42.9%) 209(26.5%) 0.001
 AMV 359(39.9%) 77(68.8%) 282(35.8%) <0.001
 Sepsis 64.0(7.1%) 12(10.7%) 52(6.6%) 0.120
 HAP 124.0(13.8%) 52(46.4%) 72(9.1%) <0.001
Time procedure
 LOS(days) 24(18, 36) 31(21, 48) 23(17.0, 34.3) <0.001
 Time of PNM occurrence (days) 8(4, 13) 10.0(6.0, 16.0) 7.0(4.0, 12.0) <0.001
 Effective treatment days (days) 5.1±7.3 6.8±10.5 4.9±6.8 0.794
Fee(Yuan) 71099.9 (50062.7, 118198.88) 137254.0 (70352.5, 230416.0) 68721.8 (48569.8, 106318.4) <0.001