Skip to main content
. 2024 Nov;76(6):1063–1088. doi: 10.1124/pharmrev.124.001195

TABLE 4.

Timing of symptom severity for a selected set of diseases There are several diseases and disorders that exhibit symptoms based on the time of day.

Disease Reference
Morning
 Rheumatoid arthritis Gibbs and Ray, 2013
 Heart attacks and myocardial infarction Muller, 1999
 Migraine headaches Fox and Davis, 1998
 Allergy Gelfand, 2004
 Infection Long et al., 2016
Evening
 Peptic ulcers Jamali et al., 1995
 Hypercholesterolemia Saito et al., 1991
 Temporomandibular joint pain van Grootel et al., 2005
 Asthma Bohadana et al., 2002
 Epilepsy Pavlova et al., 2004