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. 2024 Oct 18;42:100874. doi: 10.1016/j.bbih.2024.100874

Table 2.

Cross-sectional Associations Between Inflammation, Pain, and Fatigue. Associations between inflammatory variables (IL-6, CRP, TNFα) and pain and fatigue, with and without the inclusion of covariates. Significant correlations (pBonferroni < .008 for Pearson's r values; p < .05 for β values) are bolded. Covariates included: age, race, gender, annual household income, BMI, beta-blockers, calcium-channel blockers, ACE inhibitors, aspirin, NSAIDs, steroids, statins, and prescription opioids.

IL-6
CRP
TNF⍺
Without Covariates
With Covariates
Without Covariates
With Covariates
Without Covariates
With Covariates
(r) (β) (r) (β) (r) (β)
PAIN 0.248 0.109 0.224 0.098 .050 x
FATIGUE 0.214 0.110 0.194 0.080 0.129 0.100