Table 4.

Binding energy (kcal/mol) of the components of BGZ and cAMP signaling pathway-associated proteins.

Compound	Docking scores (kcal/mol)
	EPAC (4MH0)	PKA (4Z83)	ERK (6G9N)	IL-1β (5R88)
Bakuchalcone	−8.16	−7.67	−8.61	−6.30
Bakuchicin	−7.05	−6.31	−7.42	−5.30
Bakuchiol	−4.09	−3.69	−4.57	−2.09
Bavachalcone	−7.66	−5.93	−8.66	−5.46
Bavachinin	−7.31	−4.20	−7.50	−4.75
Corylidin	−5.81	−5.95	−6.34	−5.97
Corylinal	−4.46	−6.39	−7.84	−5.57
Delphinidin	−5.66	−5.74	−8.25	−5.54
Isobavachalcone	−7.32	−5.81	−7.94	−5.43
Isoneobavachalcone	−8.07	−6.53	−6.35	−5.64
Isopsoralen	−6.83	−7.09	−6.85	−5.28
Neobavachalcone	−8.11	−6.33	−6.27	−5.31
Neobavaisoflavone	−4.98	−7.19	−8.14	−4.46
Psoralen	−7.24	−7.08	−7.06	−5.20
Psoralenol	−6.12	−8.19	−7.38	−5.42
Psoralidin	−5.39	−5.79	−6.71	−5.35